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Rheumatology 2002; 41: 948-950
© 2002 British Society for Rheumatology

Letters to the Editor

Successful treatment of optic neuropathy in osteitis deformans

C. Isasi, J. Sanz, M. Hijós, M. Vaquero, G. Saucedo and J. L. Andreu

Department of Rheumatology, Clinica Puerta de Hierro, San Martin de Porres 4, 28035 Madrid, Spain

The first 10% of the full text of this article appears below.

SIR, Optic nerve involvement is a known, although seldom reported, complication of Paget's disease of bone. A well-documented response to treatment has not been published. We report a case of severe visual loss with long-lasting recovery after treatment with pamidronate and dexamethasone.

The patient was a 68-yr-old man whose Paget's polyostotic disease was diagnosed in 1990. The skull and a number of other bones were affected. He had been treated with calcitonin and etidronate for 6 yr and had shown an incomplete clinical and biochemical response. In October 1996 he developed progressive weakness and paraesthesias in his lower extremities. MRI . . . [Full Text of this Article]


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