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Rheumatology 2003; 42: 488-490
© 2003 British Society for Rheumatology

Letters to the Editor

A case of acquired partial lipodystrophy associated with POEMS syndrome

P. Caramaschi, D. Biasi, M. Lestani1 and M. Chilosi1

Dipartimento di Medicina Clinica e Sperimentale and
1 Istituto di Istologia ed Anatomia Patologica, Università di Verona, Italy

The first 10% of the full text of this article appears below.

SIR, A 45-yr-old woman presented with partial lipodystrophy (PL) at the age of 35 yr, characterized by the disappearance of fat at the cheeks, upper limbs and trunk. In 1996 she came to our observation; undifferentiated connective tissue disease was diagnosed on the basis of Raynaud's phenomenon, dry eyes, positivity of antinuclear antibodies (titre of 1:80 with speckled pattern), lupus anticoagulant and anticardiolipin of IgM class (9.9 U/ml). The physical examination revealed partial symmetric lipodystrophy, hypertrichosis and diffuse hyperpigmentation. Full blood count, erythrocyte sedimentation rate, transaminases, creatinine, glucose, insulin . . . [Full Text of this Article]


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