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Rheumatology 2003; 42: 797-798
© 2003 British Society for Rheumatology

Letters to the Editor

Cryofibrinogenaemia complicated by amyloidosis: a new association

S. G. Ong, C. Harrow, M. S. Devgun1 and M. Field

Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER and
1 Biochemistry Department, Wishaw General Hospital, 50 Netherton Street, Wishaw ML2 0DP, UK

The first 10% of the full text of this article appears below.

SIR, Cryofibrinogen was first described in 1955 by Korst and Kratochvil [1]. It refers to a plasma complex of fibrin, fibrinogen and fibronectin that precipitates in plasma cooled to 4°C and may dissolve upon warming to 37°C. Cryofibrinogenaemia may occur as a primary event or secondarily to a wide range of diseases, including carcinoma, acute and chronic inflammatory processes, collagen vascular diseases and thromboembolic disorders, but the aetiology of this condition remains obscure.

We report a patient with cryofibrinogenaemia who initially responded to stanozolol and then developed significant . . . [Full Text of this Article]


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