Rheumatology 2003; 42: 803-804
© 2003 British Society for Rheumatology
Letters to the Editor |
Reply
Department of Rheumatology, St Helens Hospital, Marshalls Cross Road, St Helens, Merseyside, UK
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We thank Dr Provenzano for his interest in our recent article, and are encouraged by his supportive findings. We are concerned about the interchangeable use of the terms methotrexate pulmonary toxicity, methotrexate pneumonitis' and chronic pulmonary fibrosis caused by methotrexate. We wish to clarify that the described complications of low-dose methotrexate are acute hypersensitivity pneumonitis, drug-induced asthma, pulmonary fibrosis, accelerated pulmonary nodulosis and infection with Pneumocystis