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Rheumatology 2003; 42: 805-807
© 2003 British Society for Rheumatology

Letters to the Editor

Antioxidant status and lipid peroxidation in seminal plasma and spermatozoa of patients with ankylosing spondylitis

S. Ozgocmen1,, S. Sogut2, E. Fadillioglu3, A. Ardicoglu4 and O. Ardicoglu1

1 Departments of Physical Medicine and Rehabilitation, Division of Rheumatology and
4 Urology, Firat University, Faculty of Medicine, Elazig and
2 Departments of Biochemistry and
3 Physiology, Inonu University, Faculty of Medicine, Malatya, Turkey

The first 10% of the full text of this article appears below.

SIR, Ankylosing spondylitis (AS) is a chronic inflammatory disease that affects predominantly young male individuals [1]. Fertility and a normal sexual life may be interrupted with functional sequealae and disease-modifying anti-rheumatic drugs (DMARDs), especially sulphasalazine. This is one of the important DMARDs in the management of AS and a well known cause of drug-induced infertility [1, 2].

Reactive oxygen species (ROS) play an important role in the pathogenesis of inflammatory joint diseases like rheumatoid arthritis (RA) and AS, and we have previously reported increased malondialdehyde (MDA), xanthine oxidase (XO) and catalase (CAT) activity in . . . [Full Text of this Article]


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