Rheumatology 2003; 42: 1109-1111
© 2003 British Society for Rheumatology
Letters to the Editor |
Unusual co-incidence of Heberden's and Bouchard's osteoarthritis, rheumatoid arthritis and haemochromatosis
Department of Internal Medicine I, Division of Rheumatology and Clinical Immunology, University Hospital of Regensburg, D-93042 Regensburg, Germany
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SIR, We report a 49-yr-old female patient presenting with symmetrical polyarthritides involving proximal interphalangelal (PIP) joints, metacarpophalangeal (MCP) joints, wrists, ankles and metatarsophalangeal (MTP) joints. The patient had been diagnosed with Heberden's and Bouchard's disease 5 years previously. At the time of first visit, the patient presented in reduced condition, with impressive swelling of all PIPs and all distal interphalangeal (DIP) joints, and less swelling of MCPs II and III. Laboratory results revealed an ESR of 15/22, a CRP of 17.1 mg/l (normal <5 mg/l) and an RF of 421 U/ml. HLA-DR4 was positive. X-rays of hand and finger joints showed joint narrowing of all PIPs and DIPs with minor erosions in PIPs III and IV. A skeletal scintigraphy revealed tracer accumulation in all DIPs, PIPs, MCPs and the left wrist. Based on the ACR criteria for
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