Rheumatology Advance Access originally published online on April 19, 2005
Rheumatology 2005 44(8):1072-1073; doi:10.1093/rheumatology/keh652
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
LETTER TO THE EDITOR |
Positive clinical and biochemical responses to anakinra in a 3-yr-old patient with cryopyrin-associated periodic syndrome (CAPS)
Departamento de Pediatría, Hospital Universitario Central de Asturias, Oviedo and 1 Servicio de Inmunología, Hospital Clínic, Barcelona, Spain
Correspondence to: J. I. Aróstegui, Servicio de Inmunología, Hospital Clínic, Villarroel, 170, 08036-Barcelona. Spain. E-mail: 30864jag@comb.es
| The first 10% of the full text of this article appears below. |
SIR, Cryopyrin-associated periodic syndromes (CAPS) consist of a subgroup among hereditary periodic fever syndromes that includes familial cold-induced autoinflammatory syndrome (FCAS; MIM no. 120100
[OMIM]
), MuckleWells syndrome (MWS; MIM no. 191900
[OMIM]
) and chronic infantile neurological, cutaneous, articular (CINCA) syndrome (MIM no. 670115), also known as neonatal-onset multisystem inflammatory disease (NOMID), representing different degrees of disease severity. All of them have been recently associated with heterozygous mutations in the CIAS1/PYPAF1/NALP3 gene, which encodes
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