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Rheumatology Advance Access originally published online on October 13, 2006
Rheumatology 2007 46(2):185-187; doi:10.1093/rheumatology/kel342
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© The Author 2006. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

EDITORIALS

Very early ‘Rheumatoid’ arthritis cohorts: limited by selection

Murat Inanc

Istanbul University, Istanbul Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey

Correspondence to: Murat Inanc, Istanbul Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Capa 34390 Istanbul, Turkey. E-mail: drinanc@istanbul.edu.tr

The first 150 words of the full text of this article appear below.

The heterogeneous course and prognosis of early arthritis (EA) patients continues to be a major challenge for clinicians involved in the management of these patients. A variable proportion of EA patients can be classified under rheumatoid arthritis (RA) or another disease (e.g. spondylarthritis and lupus) during the follow-up, while others remain undifferentiated or resolve spontaneously. In cohort studies of EA, the cumulative prevalence of RA varied significantly and was reported between 7 and 42%, which indicates that selection factors may influence the outcome of such cohorts [1].

Identifying EA patients at risk for developing persistent and/or erosive arthritis is mandatory for selecting a treatment strategy according to the current early aggressive treatment approach [2]. It has been widely discussed that the current ACR 1987 classification criteria for RA is not an appropriate tool for treatment purposes in the very early phase of the disease mainly because . . . [Full Text of this Article]

The effect of patient recruitment and lost-to follow-ups in EA cohort studies

Use of RA classification criteria in EA cohorts

Anti-CCP test in guiding the management of ERA

Radiological outcome of patients with EA

Conclusion


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