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Rheumatology 2008 47(11):1595-1596; doi:10.1093/rheumatology/ken393
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

EDITORIALS

Clinical trial registration

R. Watts1,2 and S. Cubie3

1Ipswich Hospital NHS Trust, Ipswich, 2School of Medicine, Health Policy and Practice, University of East Anglia, Norwich and 3British Society for Rheumatology, London, UK

Correspondence to: R. Watts, British Society for Rheumatology, Bride House, 18-20 Bride Lane, London EC4Y 8EE, UK. E-mail: editorial@rheumatology.org.uk

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Randomized clinical trials are a fundamental part of the process by which new medical knowledge is acquired and translated into clinical practice. Patients volunteer to participate in clinical trials in good faith that the results will be made available as quickly and as openly as possible to the medical community and that their participation will contribute to improved health for others. Unfortunately, in practice this does not always happen. One of the major reasons is failure to publish the complete data set, in particular when the trial has produced results suggesting that the treatment under investigation is less effective or only marginally more effective than the comparator treatment. . . . [Full Text of this Article]


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