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Rheumatology Advance Access originally published online on February 26, 2008
Rheumatology 2008 47(4):553-554; doi:10.1093/rheumatology/ken008
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Association of Kikuchi–Fujimoto's disease with SLE

F. Goldblatt1, J. Andrews2, A. Russell2 and D. Isenberg1

1Centre for Rheumatology, Department of Medicine, University College London Hospital and 2Arthritis Centre, Northwick Park Hospital, Imperial College London, UK.

Correspondence to: F. Goldblatt, Centre for Rheumatology, Department of Medicine, University College London Hospital, 3rd Floor Central, 250 Euston Road, London NW1 2PQ, UK. E-mail: fgoldblatt@ntlworld.com

The first 10% of the full text of this article appears below.

SIR, Kikuchi–Fujimoto's disease (KFD) is a rare benign form of necrotizing histiocytic lymphadenitis, typically affecting young women of Asian background. Clinical features include lymphadenopathy, predominantly involving cervical lymph nodes, fever, malaise, anorexia, myalgias and arthralgias [1]. Diagnosis is dependent upon presence of appropriate immunohistology of the lymph node, which typically shows abundant CD68+ plasmacytoid monocytes in the node paracortex, eosinophilic fibrinoid material and apoptotic debris [2]. KFD has been reported in association with a number of autoimmune and infectious diseases [3, 4], including infrequent co-existence . . . [Full Text of this Article]


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