Rheumatology Advance Access originally published online on March 17, 2008
Rheumatology 2008 47(5):731-732; doi:10.1093/rheumatology/ken091
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
LETTERS TO THE EDITOR |
Do TNF-blockers reduce or induce uveitis?
1Department of Rheumatology and 2Department of Biostatistics, Hospital Universitario La Paz, Madrid, Spain.
Correspondence to: T. Cobo-Ibáñez, Department of Rheumatology, Hospital Universitario La Paz. Po Castellana 261. 28046 Madrid, Spain. E-mail: tcoboiba@yahoo.es
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SIR, Uveitis is a well-known manifestation of SpAs that may lead to functional impairment. TNF-blockers are effective for treating SpA-related uveitis flares [1], but recent retrospective studies support the possibility of differential TNF-blockers effectiveness, with infliximab or adalimumab showing a higher efficacy than etanercept in the treatment of uveitis [2–4]. In addition, Lim et al. [5] have recently published the finding that etanercept may induce new uveitis flares. During the last 2 years, we have conducted a study with the objective of