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Rheumatology Advance Access originally published online on April 1, 2008
Rheumatology 2008 47(5):739-740; doi:10.1093/rheumatology/ken088
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Central nervous system Aspergillus fumigatus presenting as cranial nerve palsy in a patient with ankylosing spondylitis on anti-TNF therapy

J. R. Slusher1, M. E. Maldonado2,3, F. Mousavi1 and C. J. Lozada2

1University of Miami/Jackson Memorial Medical Center, 2University of Miami Miller School of Medicine, 3Miami Veterans Affairs Medical Center, Miami, FL, USA.

Correspondence to: C. J. Lozada, 1120 N.W. 14th Street, Suite 973, Miami, FL 33136, USA. E-mail: clozada@med.miami.edu

The first 10% of the full text of this article appears below.

SIR, A 52-yr-old black male with a 4-yr history of AS and mild apical pulmonary fibrosis previously responsive only to oral corticosteroids was started on etanercept 25 mg subcutaneously twice a week with excellent clinical response.

At 18 months of treatment with etanercept, the patient developed fevers, weight loss and night sweats. Etanercept therapy was immediately discontinued and work-up initiated for possible infectious aetiology. Prednisolone 12.5 mg/day and NSAIDs were continued.

The patient then developed right-sided facial pain and a sensation of inner-ear pressure with . . . [Full Text of this Article]


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