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Rheumatology Advance Access originally published online on April 14, 2008
Rheumatology 2008 47(6):929-930; doi:10.1093/rheumatology/ken129
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Successful treatment of rheumatoid vasculitis-associated cutaneous ulcers using rituximab in two patients with rheumatoid arthritis

M. Hellmann, N. Jung, K. Owczarczyk, M. Hallek and A. Rubbert

Department of Internal Medicine I, Division of Immunology and Rheumatology, University of Cologne, Cologne, Germany

Correspondence to: M. Hellmann, Department of Internal Medicine I, Division of Immunology and Rheumatology, University of Cologne, 50937 Cologne, Germany. E-mail: matthias.hellmann@uk-koeln.de

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SIR, The course of RA may be complicated by rheumatoid vasculitis (RV), at least in a subset of patients who typically present with high titres of RFs [1]. RV has a predilection for the skin and may result in peripheral gangrene and deep cutaneous ulcers that tend to occur in unusual locations. Treatment mainly consists of the use of high-dose corticosteroids in addition to DMARDs, but controlled clinical trials are missing [2]. More recently, the successful use of TNF inhibitors in selected . . . [Full Text of this Article]


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