Rheumatology Advance Access originally published online on February 7, 2009
Rheumatology 2009 48(4):330-331; doi:10.1093/rheumatology/kep002
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© The Author 2009. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
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The eyes have it! The need to improve awareness and access to early ophthalmological screening for juvenile idiopathic arthritis associated uveitis
1Musculoskeletal Research Group, Newcastle University, 2Paediatric Rheumatology, Newcastle Hospitals NHS Trust, Newcastle upon Tyne and 3Paediatric Rheumatology, Royal Bristol Children's Hospital and Royal National Hospital for Rheumatic Diseases, Bristol, UK
Correspondence to: Helen Foster, Musculoskeletal Research Group, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK. E-mail: h.e.foster@ncl.ac.uk
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Juvenile idiopathic arthritis (JIA) is a heterogeneous group of diseases that differ considerably from adult RA with different clinical, serological and genetic associations [1]. JIA is the commonest cause of acquired chronic disability in children and a major cause of visual loss in children as a result of uveitis. The association between JIA and uveitis is important because visual complications are common (up to 40% of children with uveitis) [2, 3], and can result in decreased visual acuity, and also blindness from untreated macular oedema, ambylopia and glaucoma. Acute anterior uveitis, presenting with a painful red eye is unusual in children and tends to associate typically with enthesitis-related arthritis and the presence of HLA-B27 [4]. The most common form of JIA-associated uveitis is chronic anterior uveitis, which is typically asymptomatic, occurs in
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E. B. NORDAL, N. T. SONGSTAD, L. BERNTSON, T. MOEN, B. STRAUME, and M. RYGG Biomarkers of Chronic Uveitis in Juvenile Idiopathic Arthritis: Predictive Value of Antihistone Antibodies and Antinuclear Antibodies J Rheumatol, August 1, 2009; 36(8): 1737 - 1743. [Abstract] [Full Text] [PDF] |
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