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Rheumatology Advance Access originally published online on July 20, 2009
Rheumatology 2009 48(9):1174-1176; doi:10.1093/rheumatology/kep210
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© The Author 2009. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Lateral medullary syndrome with anti-neuronal antibodies (anti-Ta/Ma2) in primary Sjögren's syndrome

Puja Mehta1, Michelle M. A. Fernando1, Matthew C. Pickering1, Yannoulla Wilson2, Sophie Molloy3 and C. Bernard Colaco4

1Molecular Genetics and Rheumatology Section, Faculty of Medicine, Imperial Academic Health Sciences Centre, London, 2Department of Immunology, Northwick Park Hospital, Harrow, 3Department of Neurology and 4Rheumatology Unit, Central Middlesex Hospital, London, UK

Correspondence to: C. Bernard Colaco, Rheumatology Unit, Central Middlesex Hospital, Acton Lane, Park Royal, London, NW10 7NS, UK. E-mail: Bernie.colaco@nwlh.nhs.uk

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SIR, A 61-year-old Irish female with known primary SS, presented to the emergency department with a 3-h history of sudden-onset vertigo, vomiting, diplopia, ataxia and hemi-facial sensory loss. She had a long-standing history of polyarthralgia and sicca symptoms with a hypergammaglobulinaemia (IgG 25g/l) and positive ANA, anti-Ro and anti-La antibodies and therefore met the diagnostic criteria for SS. Six months earlier she had an acute psychotic episode secondary to cerebral vasculitis with cerebrospinal fluid (CSF) oligoclonal bands and three small hyperintense foci in the frontal lobe on MRI . . . [Full Text of this Article]


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