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Rheumatology 2009 48(Supplement 4):iv1-iv2; doi:10.1093/rheumatology/kep277
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© The Author 2009. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Editorial

Strontium ranelate: new perspectives for the management of osteoporosis

Bernard Cortet1

1Department of Rheumatology, University-Hospital of Lille, University of Lille II, Lille cedex, France

Correspondence to: Bernard Cortet, Department of Rheumatology, University-Hospital of Lille, University of Lille II, 59045 Lille cedex, France. E-mail: bcortet@chru-lille.fr

The first 10% of the full text of this article appears below.

Osteoporosis is a complex disease characterized by low bone mass and also alterations of bone quality leading to an increased fracture risk. The increasing worldwide incidence of osteoporosis requires the use of effective treatments.

Several classes of drugs are used in the prevention of osteoporosis-related fractures with proven clinical efficacy, mostly on vertebral fractures and more rarely on non-vertebral and hip fractures. Anti-resorptive agents are the most represented. The most numerous among them are bisphosphonates. They act by reducing not only bone resorption, but also bone formation due to the coupling between bone . . . [Full Text of this Article]


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