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Rheumatology Advance Access published online on April 16, 2008
Rheumatology, doi:10.1093/rheumatology/ken143
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Efficacy and safety of rituximab in a patient with active rheumatoid arthritis and chronic disseminated pulmonary aspergillosis and history of tuberculosis

N. Jung*, K. Owczarczyk*, M. Hellmann, C. Lehmann, G. Fätkenheuer, M. Hallek and A. Rubbert

Department of Internal Medicine I, Division of Immunology and Rheumatology, University of Cologne, Cologne, Germany

Correspondence to: N. Jung, Department of Internal Medicine I, Division of Immunology and Rheumatology, University of Cologne, Kerpener Str. 62, 50935 Cologne, Germany. E-mail: norma.jung@uni-koeln.de

The first 10% of the full text of this article appears below.

SIR, In RA, the rate of infections and infection-related mortality is up to 4 to 6 times higher as compared with the general population [1] and an increased risk has been associated in particular with the use of steroids [2] and TNF inhibitors [3]. Therefore, treatment of RA in patients with underlying chronic infections represents a challenge given that therapeutic options are limited.

We here report on a patient with active RA, who developed tuberculosis during . . . [Full Text of this Article]


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