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Rheumatology Advance Access published online on October 1, 2009
Rheumatology, doi:10.1093/rheumatology/kep309
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© The Author 2009. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

A retrospective clinical analysis of pharmacological modalities used for symptomatic relief of Raynaud's phenomenon in children treated in a UK paediatric rheumatology centre

Kapil Gargh1, Eileen M. Baildam1, Gavin A. Cleary1, Michael W. Beresford1 and Liza J. Mccann1

1Department of Paediatric Rheumatology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK

Correspondence to: Correspondence to: Liza McCann, Department of Paediatric Rheumatology, Alder Hey Children's NHS Foundation Trust, Eaton Road, Liverpool, L12 2AP, UK. E-mail: liza.mccann@alderhey.nhs.uk

The first 10% of the full text of this article appears below.

SIR, Need for pharmacological treatment of RP depends on symptom severity, patient distress and presence of underlying disease. Many treatment modalities, without gold standard, are reported in adults. Paediatric studies are scarce. Calcium channel blockers (nifedipine or amlodipine) are favoured, but response is variable and adverse events occur. Glyceryl trinitrate (GTN) has been used in adults as topical ointment [1, 2] or patches [3], but to date, no studies document paediatric use.

We surveyed treatment outcomes of RP within a secondary/tertiary . . . [Full Text of this Article]


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