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© 1986 British Society for Rheumatology

research-article

RADIOGRAPHIC TEMPOROMANDIBULAR JOINT ABNORMALITIES IN PATIENTS WITH JUVENILE CHRONIC ARTHRITIS DURING A CONTROLLED STUDY OF SODIUM AUROTHIOMALATE AND D-PENICILLAMINE

T. K. KVIEN1,, T. A. LARHEIM2, H. M. HØYERAAL1 and B. SANDSTAD3

1Paediatric Division, Oslo Sanitetsforening Rheumatism Hospital Norway
2Department of Oral Radiology, Dental Faculty, University of Oslo Norway
3University of Oslo Norway

Correspondence to: Address correspondence to Dr. T. K. Kvien, Paediatric Division, Oslo Sanitetsforening Rheumatism Hospital, Akersbakken 27, 0172 Oslo 1, Norway

Sixty-two patients with juvenile chronic arthritis (JCA) were randomized to 50-week treatment with either sodium aurothiomalate (G) or D-penicillamine (PEN) and followed with regard to radiographic changes of the temporomandibular joints (TMJ). The radiographic methods comprised panoramic radiography and oblique lateral transcranial radiography, occasionally supplemented with other methods. The radiographs were read by a single assessor who did not know the type of drug treatment. Radiographic progression was seen in one G-treated and six PEN-treated patients with polyarticular JCA. and in one G-treated patient with pauci-articular JCA. A relation between changes in radiographic TMJ findings and disease activity was demonstrated. Radiographic examination of the TMJ seems to be of value in therapeutic trials in patients with JCA.

KEY WORDS: Juvenile chronic arthritis, Temporomandibular joint, Radiography, Gold, Penicillamine


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