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© 1988 British Society for Rheumatology

brief-report

BRIEF REPORT THE NATURAL HISTORY OF JUVENILE-ONSET ANKYLOSING SPONDYLITIS: A 24-YEAR RETROSPECTIVE CASE-CONTROL STUDY

A. CALIN and JUDITH ELSWOOD

Royal National Hospital for Rheumatic Diseases Upper Borough Walls, Bath BA1 1RL, UK

Correspondence to: Address correspondence to Dr. Calin.

One hundred and thirty-five patients with juvenile-onset ankylosing spondylitis (JAS: <16 years at onset, mean 12.8 years) were compared to 135 adult-onset spondylitics (AAS: >21 years at onset, mean 26.1 years), controlled for disease duration (24.5 and 23.5 years, respectively), to assess the outcome of juvenile-onset disease. Review was by postal questionnaire and health-assessment measures. The sex distribution was similar: 73% and 74% males, respectively. All parameters showed comparable outcome with the exception of the numbers in full-time employment (JAS 74%, AAS 56%; p < 0.01) and total hip replacements (JAS 17%, AAS 4%; p < 0.01). In conclusion: (a) the premature hip is particularly at risk in ankylosing spondylitis; (b) there are few differences between the outcome of JAS and AAS; (c) overall, JAS patients do well in adulthood.

KEY WORDS: Juvenile arthritis, Hip disease, Hip replacement, Prognosis.


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