Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by DOLAN, A. L.
Right arrow Articles by KINGSLEY, G. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by DOLAN, A. L.
Right arrow Articles by KINGSLEY, G. H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1995 British Society for Rheumatology

case-report

DILTIAZEM INDUCES REMISSION OF CALCINOSIS IN SCLERODERMA

A. L. DOLAN, D. KASSIMOS, T. GIBSON and G. H. KINGSLEY

Department of Rheumatology, Guy's Hospital London SE1 9RT

Correspondence to: Correspondce to: G. H. Kingsley, Rheumatology Unit, 4th Floor, Hunts House, Guy's Hospital, London SEl 9RT.

There is no widely accepted treatment for the calcinosis which occurs in scleroderma and dermatomyositis. We report a case of a 62-yr-old woman with active scleroderma complicated by tuberose calcinosis. The calcinosis, which had previously been unchanged for several years, regressed over a 2-yr period during which diltiazem was used to treat hypertension. This effect could not be explained by altered disease activity or renal function but, we suggest, may be due to inhibition of calcium influx into cells. This treatment merits further evaluation.

KEY WORDS: Systemic sclerosis, Calcinosis, Treatment, Diltiazem


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Ann Rheum DisHome page
J Avouac, H Guerini, J Wipff, N Assous, A Chevrot, A Kahan, and Y Allanore
Radiological hand involvement in systemic sclerosis
Ann Rheum Dis, August 1, 2006; 65(8): 1088 - 1092.
[Abstract] [Full Text] [PDF]

Home page
 Ann Rheum DisHome page
T Cukierman, E Elinav, M Korem, and T Chajek-Shaul
Low dose warfarin treatment for calcinosis in patients with systemic sclerosis
Ann Rheum Dis, October 1, 2004; 63(10): 1341 - 1343.
[Abstract] [Full Text] [PDF]

Home page
 Ann Rheum DisHome page
L P Robertson, R W Marshall, and P Hickling
Treatment of cutaneous calcinosis in limited systemic sclerosis with minocycline
Ann Rheum Dis, March 1, 2003; 62(3): 267 - 269.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
C. S. Vinen, S. Patel, and F. E. Bruckner
Regression of calcinosis associated with adult dermatomyositis following diltiazem therapy
Rheumatology, March 1, 2000; 39(3): 333 - 334.
[Full Text] [PDF]

Home page
 Ann Rheum DisHome page
G. D Wright

Ann Rheum Dis, September 1, 1999; 58(9): 523 - 523.
[Full Text]

Home page
 Ann Rheum DisHome page
M Vayssairat, D Hidouche, N Abdoucheli-Baudot, and J P Gaitz
Clinical significance of subcutaneous calcinosis in patients with systemic sclerosis. Does diltiazem induce its regression?
Ann Rheum Dis, April 1, 1998; 57(4): 252 - 254.
[Abstract] [Full Text]

Home page
 J. Clin. Endocrinol. Metab.Home page
M. C. Eddy, R. Leelawattana, W. H. McAlister, and M. P. Whyte
Calcinosis Universalis Complicating Juvenile Dermatomyositis: Resolution During Probenecid Therapy
J. Clin. Endocrinol. Metab., November 1, 1997; 82(11): 3536 - 3542.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.