Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Harrison, B. J.
Right arrow Articles by Symmons, D. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Harrison, B. J.
Right arrow Articles by Symmons, D. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

The British Journal of Rheumatology, Vol 36, 366-369, Copyright © 1997 by British Society for Rheumatology

ORIGINAL PAPERS

Patients who develop inflammatory polyarthritis (IP) after immunization are clinically indistinguishable from other patients with IP

BJ Harrison, W Thomson, L Pepper, WE Ollier, K Chakravarty, EM Barrett, AJ Silman and DP Symmons
ARC Epidemiology Research Unit, Manchester.

Musculoskeletal symptoms may occur following various types of immunization, and it has also been suggested that, like infection, immunization may act as a trigger for rheumatoid arthritis (RA). A total of 48 of 898 (5.3%) patients with early inflammatory polyarthritis (IP) referred to the Norfolk Arthritis Register reported an immunization in the 6 weeks prior to symptom onset. There were no important clinical or demographic differences between the 48 immunized patients and 185 consecutive patients who did not report prior immunization. In addition, the frequencies of HLA-DRB1*01. *04 and the shared epitope in 33 of the immunized patients were similar to those in the 185 non-immunized patients and to those in 136 healthy controls. Further results from a case-control study suggest that the rate of immunization is higher amongst cases (5.5%) than age- and sex-matched controls (2.8%). In a small number of susceptible individuals, immunization may thus act as a trigger for RA.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Ann Rheum DisHome page
E Pattison, B J Harrison, C E M Griffiths, A J Silman, and I N Bruce
Environmental risk factors for the development of psoriatic arthritis: results from a case-control study
Ann Rheum Dis, May 1, 2008; 67(5): 672 - 676.
[Abstract] [Full Text] [PDF]

Home page
 Ann Rheum DisHome page
J Sibilia and J F Maillefert
Vaccination and rheumatoid arthritis
Ann Rheum Dis, July 1, 2002; 61(7): 575 - 576.
[Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
D. Symmons and B. Harrison
Early inflammatory polyarthritis: results from the Norfolk Arthritis Register with a review of the literature. I. Risk factors for the development of inflammatory polyarthritis and rheumatoid arthritis
Rheumatology, August 1, 2000; 39(8): 835 - 843.
[Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
J. F. Maillefert, J. Sibilia, E. Toussirot, E. Vignon, J. P. Eschard, B. Lorcerie, R. Juvin, N. Parchin-Geneste, C. Piroth, D. Wendling, et al.
Rheumatic disorders developed after hepatitis B vaccination
Rheumatology, October 1, 1999; 38(10): 978 - 983.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.