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Rheumatology 1999; 38: 1017-1018
© 1999 British Society for Rheumatology

Letters to the Editor

Drug-induced lupus nephritis in HIV infection

P. R. Smith , D. D'cruz 1, M. J. Raftery 2, S. M. Dodd 3, M. Helbert 4 and C. J. Skinner

Department of Genito-Urinary Medicine,
1 Department of Rheumatology,
2 Department of Renal Medicine,
3 Department of Morbid Anatomy and
4 Department of Immunology, Royal Hospitals NHS Trust, London, UK

Correspondence to: C. J. Skinner, Department of Genito-Urinary Medicine, The Royal London Hospital, Whitechapel, London E1 1BB, UK.

SIR, A 39-yr-old Zambian woman, living in the UK for 1 yr, was admitted to another hospital with chronic diarrhoea. A rectal biopsy demonstrated granuloma formation and therapy was initiated on a presumptive basis for tuberculosis and Crohn's disease with mesalazine, rifampicin and isoniazid. Eleven months later, she was found to be HIV positive by ELISA, and 6 weeks later was admitted to our hospital with a 1 month history of arthralgia involving the shoulders, wrists, hands, knees and feet, and an intermittent fever. There was no history of joint swelling, haematuria or oliguria.

On examination, she was apyrexial . . . [Full Text of this Article]

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