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Rheumatology 1999; 38: 1285-1289
© 1999 British Society for Rheumatology

Grand Rounds in Rheumatology

Organizing pneumonia associated with pulmonary artery aneurysms in Behçet's disease

A. Gül, D. Yilmazbayhan1, N. Büyükbabani1, J. T. Lie2,{dagger}, M. Tunaci3, A. Tunaci3, M. Inanç, L. Öcal, O. Aral and M. Koniçe

Division of Rheumatology, Department of Internal Medicine,
1 Department of Pathology and
3 Department of Radiology, Istanbul School of Medicine, Istanbul, Turkey and
2 Division of Anatomic Pathology, Davis School of Medicine, University of California, Sacramento, CA, USA

Correspondence to: A. Gül, Zuhuratbaba mah. Türkis cad. No: 14/8, Bakirköy 34740, Istanbul, Turkey.

KEY WORDS: Behçet's disease, Pulmonary artery aneurysm, Pulmonary vasculitis, Bronchiolitis obliterans organizing pneumonia, Organizing pneumonia, Peripheral pulmonary opacities

Behçet's disease (BD) is a relapsing chronic inflammatory disorder of unknown aetiology. Although BD has originally been described as a triad of recurrent oral aphthous ulceration, genital ulceration and uveitis, it is now recognized as a multisystem disease with vasculitis as the main pathological finding [1].

Involvement of the lungs is a rare feature of BD [2–6]. Pulmonary artery aneurysm (PAA) is the best-defined type of pulmonary disease in BD with an important morbidity and mortality [5]. After the widespread use of computed tomographic (CT) and magnetic resonance imaging (MRI) methods, more BD patients with pulmonary parenchymal changes have been noted. However, the pulmonary parenchymal involvement in BD still needs to be explored fully [6].

Herein, we describe a patient with BD who developed multiple PAA and died of massive haemoptysis, and discuss the pathological correlation of his peripheral pulmonary . . . [Full Text of this Article]

Case report

Discussion

Pulmonary involvement in BD
BOOP and pulmonary vasculitis in BD
Diagnosis and differential diagnosis of BOOP in BD
Treatment and prognosis of patients with BOOP

Concluding remarks

Notes

References


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