Rheumatology, Vol 38, 411-414, Copyright © 1999 by British Society for Rheumatology
T Hannu, M Puolakkainen and M Leirisalo-Repo
OBJECTIVE: To determine the role of Chlamydia pneumoniae as a triggering
infection in reactive arthritis (ReA). METHODS: Sixty patients with acute
arthritis were screened for the evidence of triggering infections. In all
patients, bacterial stool cultures, culture of Chlamydia trachomatis in
urethra/cervix, and/or bacterial serology were studied. Chlamydia
pneumoniae antibodies were measured by specific microimmunofluorescence
test. RESULTS: Thirty-five of 60 patients fulfilled the diagnostic criteria
for ReA. Thirty-one patients had microbial/serological evidence of
preceding infection due to Salmonella, Yersinia, Campylobacter or Chlamydia
trachomatis, or they had enteritis or urethritis prior to arthritis. Four
additional patients had high antibody titre for C. pneumoniae. Three of
these four patients had preceding lower respiratory symptoms, and were
positive for HLA-B27. The clinical picture of C. pneumoniae-positive ReA
patients was similar to that of ReA patients with other definite aetiology.
CONCLUSION: Chlamydia pneumoniae is a triggering factor in approximately
10% of patients with acute ReA.
ORIGINAL PAPERS
Chlamydia pneumoniae as a triggering infection in reactive arthritis
Department of Medicine, Helsinki University Central Hospital, Finland.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  C. S. Little, A. Bowe, R. Lin, J. Litsky, R. M. Fogel, B. J. Balin, and K. L. Fresa-Dillon Age Alterations in Extent and Severity of Experimental Intranasal Infection with Chlamydophila pneumoniae in BALB/c Mice Infect. Immun., March 1, 2005; 73(3): 1723 - 1734. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Altun, O. Kasapcopur, M. Aslan, S. Karaarslan, V. Koksal, S. Saribas, S. Ergin, N. Arisoy, and B. Kocazeybek Is there any relationship between Chlamydophila pneumoniae infection and juvenile idiopathic arthritis? J. Med. Microbiol., August 1, 2004; 53(8): 787 - 790. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. Colmegna, R. Cuchacovich, and L. R. Espinoza HLA-B27-Associated Reactive Arthritis: Pathogenetic and Clinical Considerations Clin. Microbiol. Rev., April 1, 2004; 17(2): 348 - 369. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Yang, W. C. Hooper, D. J. Phillips, M. L. Tondella, and D. F. Talkington Induction of Proinflammatory Cytokines in Human Lung Epithelial Cells during Chlamydia pneumoniae Infection Infect. Immun., February 1, 2003; 71(2): 614 - 620. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J Sibilia and F-X Limbach Reactive arthritis or chronic infectious arthritis? Ann Rheum Dis, July 1, 2002; 61(7): 580 - 587. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. A. Khan Update on Spondyloarthropathies Ann Intern Med, June 18, 2002; 136(12): 896 - 907. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Huhtinen, M. Puolakkainen, K. Laasila, M. Sarvas, A. Karma, and M. Leirisalo-Repo Chlamydial Antibodies in Patients with Previous Acute Anterior Uveitis Invest. Ophthalmol. Vis. Sci., July 1, 2001; 42(8): 1816 - 1819. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C Fendler, S Laitko, H Sorensen, C Gripenberg-Lerche, A Groh, J Uksila, K Granfors, J Braun, and J Sieper Frequency of triggering bacteria in patients with reactive arthritis and undifferentiated oligoarthritis and the relative importance of the tests used for diagnosis Ann Rheum Dis, April 1, 2001; 60(4): 337 - 343. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D Taylor-Robinson and A Keat How can a causal role for small bacteria in chronic inflammatory arthritides be established or refuted? Ann Rheum Dis, March 1, 2001; 60(3): 177 - 185. [Full Text] [PDF]
|
|
|
|
|
|
P. Toivanen and A. Toivanen Two forms of reactive arthritis? Ann Rheum Dis, December 1, 1999; 58(12): 737 - 741. [Abstract] [Full Text]
|
|