Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (11)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Maclachlan, D.
Right arrow Articles by Tyndall, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Maclachlan, D.
Right arrow Articles by Tyndall, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Rheumatology 2000; 39: 106-108
© 2000 British Society for Rheumatology

Letters to the Editor

Successful treatment of hepatitis B-associated polyarteritis nodosa with a combination of lamivudine and conventional immunosuppressive therapy: a case report

D. Maclachlan, M. Battegay1, A. L. Jacob2 and A. Tyndall

University Department of Rheumatology, Felix Platter Spital, Burgfelder Strasse 101, Basel,
1 University Medical Outpatient Department and
2 University Institute of Diagnostic Radiology, Kantonsspital Basel, Petersgraben 4, Basel, Switzerland

Correspondence to: D. Maclachlan, University Department of Rheumatology, Felix Platter Spital, Burgfelder Strasse 101, CH-4055 Basel, Switzerland.

SIR, Treatment of hepatitis B virus (HBV)-associated polyarteritis nodosa with immunosuppression is problematic due to possible enhancement of viral replication [1], which may also possibly worsen the vasculitis by enhancing viral antigenaemia.

Lamivudine has recently been shown to suppress the replication of HBV by >98% [2–5] and could thus allow the use of conventional immunosuppressive agents to control the vasculitis. We report the case of a patient treated successfully in this manner.

The patient, a general surgeon, developed diffuse myalgias . . . [Full Text of this Article]

References


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Rheumatology (Oxford)Home page
A. Filer, A. Hughes, K. Kane, D. Mutimer, P. Jobanputra, D. Maclachlan, M. Battegay, A. L. Jacob, and A. Tyndall
Successful treatment of hepatitis B-associated vasculitis using lamivudine as the sole therapeutic agent
Rheumatology, September 1, 2001; 40(9): 1064 - 1065.
[Full Text] [PDF]