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Rheumatology 2000; 39: 1286-1287
© 2000 British Society for Rheumatology

Letters to the Editor

Rheumatoid arthritis in ß-thalassaemia trait

G. Castellino, M. Govoni and F. Trotta

Divisione di Reumatologia, Azienda Ospedaliera Arcispedale Sant' Anna, Ferrara, Italy

The first 10% of the full text of this article appears below.

SIR, We read with great interest the letter by Montecucco et al. [1]. They concluded that subjects with the ß-thalassaemia (ß-thal) trait have a high prevalence of polyarthritis resembling rheumatoid arthritis (RA), but not of other inflammatory rheumatic diseases, such as connective tissue disease and seronegative spondyloarthrytis. They also stated that the so-called arthritis of the ß-thal trait is probably not a distinct clinical entity, as previously thought, and may be regarded as a mild form of seronegative RA. We reached the same conclusion in our own studies of this topic.

In our original report, published in 1975 [2], we studied the incidence of the ß-thal trait (confirmed by haemoglobin electrophoresis) in 146 RA patients consecutively admitted to the hospital, . . . [Full Text of this Article]

C. Montecucco and R. Caporali

Servizio di Reumatologia, IRCCS Policlinico S. Matteo, 27100 Pavia, Italy


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