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Rheumatology 2000; 39: 209-210
© 2000 British Society for Rheumatology

Paediatric Rheumatology

Factor V Leiden and venous thrombosis in a 4-yr-old girl with Behçet's syndrome

J. Ihle3, J. Kümmerle-Deschner, T. Orlikowsky, E. Albert1, D. Niethammer and G. E. Dannecker

Universitätskinderklinik, Hoppe-Seyler-Straße 1, D-72076 Tübingen and
1 Labor für Immungenetik, Poliklinik der Universität München, Pettenkoferstraße 8a, D-80336 München, Germany

Sir, Behçet's syndrome (BS) was originally described as a triad of aphthous stomatitis, genital ulcers and iritis, but many additional manifestations of the disease are well known. The aetiology is unknown, but an association with HLA-B51 has been described in patients of Oriental and Mediterranean origin. In Japanese patients with BS, an association with MIC-A*009 (MHC class I chain-related gene A), which is even stronger than that with HLA-B51, has been reported recently [1].

Onset of BS in childhood is very rare and the most common clinical manifestation in the paediatric age . . . [Full Text of this Article]

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