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Rheumatology 2001; 40: 1426-1427
© 2001 British Society for Rheumatology

Letters to the Editor

Cigarette smoking and severity of rheumatoid arthritis

D. Hutchinson and R. Moots

Department of Medicine, Clinical Sciences Centre, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK

SIR, We read with great interest the paper by Masdottir et al. [1] reporting that women with rheumatoid arthritis (RA) and considerable exposure to cigarette smoke were more likely to have severe disease and nodules than women who smoked modestly. However, we propose that heavy prolonged smoking is also associated with the development of seropositive RA rather than simply disease severity (in terms of joint damage) and that the development of rheumatoid factor (RF) in . . . [Full Text of this Article]

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