Skip Navigation

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (12)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Melikoglu, M.
Right arrow Articles by Yazici, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Melikoglu, M.
Right arrow Articles by Yazici, H.
Related Collections
Right arrow Vasculitis
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Rheumatology 2001; 40: 212-215
© 2001 British Society for Rheumatology

A reappraisal of amyloidosis in Behçet's syndrome

M. Melikoglu, M. R. Altiparmak1, I. Fresko, R. Tunç, S. Yurdakul, V. Hamuryudan and H. Yazici

Departments of Rheumatology and
1 Nephrology, Cerrahpasa Medical School, University of Istanbul, Istanbul, Turkey

Objective. To evaluate the clinical features and outcome of patients with Behçet's syndrome (BS) and amyloidosis and to assess the associated risk factors.

Method. A chart review was done to determine the frequency of amyloidosis in BS among 4000 patients. Data from 14 BS patients with amyloidosis were compared with data obtained from 718 patients with BS without amyloidosis. Multiple stepwise logistic regression analysis was used to assess the risk factors.

Results. All patients with amyloidosis presented with the nephrotic syndrome or significant proteinuria. The mean time to the onset of amyloidosis was 8.1 yr (range 3–15 yr). The mean duration of follow-up after amyloidosis was 3.4 yr (range 1–11 yr). Seven out of 14 patients were alive at the time of the evaluation. Peripheral and pulmonary arterial involvement and arthritis were associated with amyloidosis (P<0.05).

Conclusion. Amyloidosis in BS is rare and has a 50% mortality rate at 3.4 yr (range 1–11 yr). Peripheral and pulmonary arterial involvement and arthritis seem to be the strongest predictors of amyloidosis in BS.

KEY WORDS: Behçet's syndrome, Amyloidosis.

Correspondence to: M. Melikoglu, Cumhuriyet sitesi, 7–8 kisim D31C D:20, Ataköy, Istanbul, Turkey.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Dent. Res.Home page
L.M. Al-Otaibi, S.R. Porter, and T.W.J. Poate
Behcet's Disease: A Review
J. Dent. Res., March 1, 2005; 84(3): 209 - 222.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
K. Aksu, H. Kocanaogullari, G. Keser, V. Inal, Y. Kabasakal, F. Oksel, G. Gumusdis, and E. Doganavsargil
A case of Behcet's disease with pulmonary arterial aneurysm and secondary amyloidosis
Rheumatology, July 1, 2002; 41(7): 831 - 832.
[Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
T. Akpolat, E. Yilmaz, I. Akpolat, M. Dilek, F. Karagoz, B. Balci, and S. Ozen
Amyloidosis in Behcet's disease and familial Mediterranean fever
Rheumatology, May 1, 2002; 41(5): 592 - 593.
[Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.