Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (21)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Stoll, T.
Right arrow Articles by Villiger, P. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stoll, T.
Right arrow Articles by Villiger, P. M.
Related Collections
Right arrow Systemic Lupus Erythematosus and Autoimmunity
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Rheumatology 2001; 40: 695-698
© 2001 British Society for Rheumatology

Original Papers

Prediction of depression in systemic lupus erythematosus patients using SF-36 Mental Health scores

T. Stoll, Y. Kauer, S. Büchi1, R. Klaghofer1, T. Sensky2 and P. M. Villiger3

Rheuma- und Rehabilitationsklinik, Schinznach,
1 Division of Psychosocial Medicine, University Hospital, Zürich, Switzerland,
2 Imperial College of Medicine, West Middlesex University Hospital, London, UK and
3 Department of Rheumatology, Clinical Immunology and Allergology, University Hospital, Bern, Switzerland

Objective. As depression is common in systemic lupus erythematosus (SLE) patients, we investigated whether and how the Medical Outcome Survey Short Form 36 (SF-36) scores, routinely used in the assessment of SLE patients, would indicate the absence or presence of depression.

Methods. The Depression subscale of the Hospital Anxiety and Depression Scale (HADS-D) and the SF-36 were applied in a cross-sectional cohort of 60 SLE patients [mean age 45 (S.D. 15) yr, disease duration 11 (9) yr, 90% female, 100% Caucasians]. The SF-36 domain score with the closest association with HADS-D was used for further analysis. On the basis of HADS-D scores, the patients were split into two groups: one without depression (score<8) and the other with possible depression (score >=8).

Results. The SF-36 Mental Health score was most closely correlated to the depression score ({rho}=-0.69, P<0.0005). The calculated Mental Health score cut-off value which significantly differentiated possibly depressed from non-depressed SLE patients was 61. Its sensitivity for the detection of possible depression was 89%, its specificity 77% and its negative predictive value 97%.

Conclusions. The present study contributes to knowledge of means of excluding depression and the prevention of underdiagnosis and undertreatment of depression in SLE patients.

KEY WORDS: SLE, SF-36, HADS, Depression.

Correspondence to: T. Stoll, Rheuma- und Rehabilitationsklinik, Badstrasse 55, CH-5116 Schinznach-Bad, Switzerland.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Adv. Psychiatr. Treat.Home page
A. Mak, R. C. M. Ho, and C. S. Lau
Clinical implications of neuropsychiatric systemic lupus erythematosus
Adv. Psychiatr. Treat., November 1, 2009; 15(6): 451 - 458.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
S. Rinaldi, A. Doria, F. Salaffi, M. Ermani, L. Iaccarino, A. Ghirardello, S. Zampieri, P. Sarzi-Puttini, P. F. Gambari, and G. Perini
Health-related quality of life in Italian patients with systemic lupus erythematosus. I. Relationship between physical and mental dimension and impact of age
Rheumatology, December 1, 2004; 43(12): 1574 - 1579.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.