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Rheumatology 2002; 41: 353-355
© 2002 British Society for Rheumatology

Letters to the Editor

Ibuprofen-induced aseptic meningoencephalitis

R. Z. Lee, O. Hardiman1 and P. G. O'Connell

Departments of Rheumatology and
1 Neurology, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland

SIR, We report the case of a 69-yr-old man, previously healthy, who became nauseated, agitated, confused and pyrexic on two occasions, within hours of consumption of ibuprofen. A diagnosis of ibuprofen-induced aseptic meningoencephalitis was made based on the patient's typical clinical and laboratory findings, the close temporal association with ibuprofen ingestion and the rapid resolution of symptoms despite discontinuation of antibiotic treatment on the latter episode. Rheumatologists should be aware of this rare but dramatic complication of a common medication.

A previously healthy 69-yr-old man presented via the Casualty Department in June 1998 with acute onset . . . [Full Text of this Article]

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