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Rheumatology 2002; 41: 355-356
© 2002 British Society for Rheumatology

Letters to the Editor

Haemorrhagic colitis due to Escherichia coli O103:H2 associated with infliximab therapy in a patient with rheumatoid arthritis

A. Kirchgatterer, T. Weber, M. Hinterreiter, P. Knoflach and F. Allerberger1

First Department of Medicine, General Hospital, Wels and
1 Institute of Hygiene and Social Medicine, University of Innsbruck, Austria

SIR, A 69-yr old woman had been diagnosed with rheumatoid arthritis (RA) 3 yr ago. She had evidence of active disease despite treatment with prednisolone (12.5–25 mg/day) and methotrexate (12.5 mg/week). As exclusion criteria were absent and informed consent had been obtained, she received a single intravenous infusion of infliximab, a chimeric monoclonal antibody against tumour necrosis factor {alpha} (TNF-{alpha}). The dose was 200 mg (3 mg/kg). The . . . [Full Text of this Article]

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