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Rheumatology 2002; 41: 470-471
© 2002 British Society for Rheumatology

Letters to the Editor

Neuromyelitis optica (Devic's syndrome) in systemic lupus erythematosus: a case report

A. N. Gibbs, J. Moroney, D. Foley-Nolan and P. G. O'Connell

Departments of Rheumatology and Neurology, Beaumont Hospital, Dublin 9 and Waterford Regional Hospital, Waterford, Ireland

SIR, In systemic lupus erythematosus (SLE), neuropsychiatric involvement is one of the main causes of morbidity and mortality. Survival drops significantly after the onset of the first neurological sign, declining to 50% after 5 yr [1]. Neuromyelitis optica is one of the rarest and most serious neurological manifestations of SLE, with about a dozen cases reported in the literature to date [2].

We report the case of a 48-yr-old Irish woman with a 3-yr history of SLE. The diagnosis was based on positivity for antinuclear factor (ANF) and anti-double-stranded DNA antibodies, photosensitivity, malar rash, Raynaud's phenomenon and non-erosive, symmetrical, inflammatory small-joint arthropathy. She presented to another . . . [Full Text of this Article]

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