Rheumatology 2003; 42: 1120-1122
© 2003 British Society for Rheumatology
Letters to the Editor |
Oestrogen receptors in cultured epithelial cells from salivary glands of Sjögren's syndrome patients
Department of Biological Chemistry and
1 Department of Pathophysiology, University of Athens, Medical School, 75 Mikras Asias, Goudi 11527, Athens, Greece
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SIR, Sjögren's syndrome (SS), or autoimmune epithelitis, is a chronic autoimmune disorder characterized by lymphoepithelial lesions of the salivary, lachrymal and other exocrine glands [1]. The disorder has a strong predilection for women in their fourth or fifth decade of life. Epithelial cells appear to play an important role in the initiation and maintenance of autoimmune lesions in SS patients, as indicated by the analysis of tissues and long-term cultured non-neoplastic salivary gland epithelial cell (SGEC) lines [1]. Recent studies from our laboratory have indicated the operation
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