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Rheumatology Advance Access originally published online on July 16, 2003
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Rheumatology 2004; 43: 100-101
© British Society for Rheumatology 2003; all rights reserved

Debates in Rheumatology

This house believes that we should advise our patients with osteoarthritis of the knee to take glucosamine

J. J. Manson and A. Rahman

Centre for Rheumatology, Department of Medicine, University College London, London, UK.

The first 150 words of the full text of this article appear below.

Introduction

Glucosamine is a natural aminomonosaccharide, which is a normal constituent of glycosaminoglycans in cartilage matrix and synovial fluid. Oral glucosamine is taken by patients with osteoarthritis in the belief that it can improve symptoms and act as a disease-modifying agent. It is not available for prescription as a drug, so that patients generally have to buy it. This can represent a significant cost. Rheumatologists have not reached a consensus as to whether the evidence in favour of glucosamine is strong enough to justify our advising patients to take it [1]. This issue was debated at the Centre for Rheumatology, University College Hospitals London NHS Trust on 6 February 2003. The debate is summarized below.

Proposition

Osteoarthritis of the knee is very common, and patients with this condition often suffer greatly from symptoms that may respond poorly to the available treatments. Some of those treatments, notably non-steroidal anti-inflammatory drugs (NSAIDs), . . . [Full Text of this Article]

Opposition

Discussion


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