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Rheumatology 2004 43(12):1587-1588; doi:10.1093/rheumatology/keh393
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Rheumatology Vol. 43 No. 12 © British Society for Rheumatology 2004; all rights reserved

LETTER TO THE EDITOR

Accelerated nodulosis during methotrexate therapy in a patient with systemic lupus erythematosus and Jaccoud's arthropathy

M.-G. Rivero, A.-J. Salvatore1, J. A. Gómez-Puerta2, J. M. Mascaró, Jr3, J. D. Cañete2, J. Muñoz-Gómez2 and R. Sanmartí2

Department of Immunology, Hospital Central, 1 Department of Internal Medicine, Hospital Lagomaggiore, Mendoza, Argentina, 2 Department of Rheumatology, 3 Department of Dermatology, Hospital Clínic, Barcelona, Spain.

Correspondence to: R. Sanmartí, Rheumatology Department, Hospital Clínic, Villarroel 170, Barcelona 08036, Catalonia, Spain. E-mail: sanmarti@clinic.ub.es

The first 10% of the full text of this article appears below.

SIR, Accelerated nodulosis (AN) is a well-known complication of methotrexate (MTX) therapy in rheumatoid arthritis (RA) patients [1], characterized by the rapid appearance of small nodules on the hands, elbows and feet [1]. Although subcutaneous nodules have been described in systemic lupus erythematosus (SLE) [2–5], we are unaware of reports of AN in SLE during MTX treatment.

We report the case of a 34-yr-old female who was referred in October 1994 to a rheumatology department . . . [Full Text of this Article]


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