Rheumatology 2004; 43: 243-244
British Society for Rheumatology 2004; all rights reserved
Letter to the Editor |
Long-term treatment of rheumatoid arthritis with tumour necrosis factor
blockade: outcome of ceasing and restarting biologicals
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, UK
Correspondence to: P. Emery, Academic Unit of Musculoskeletal Disease, 1st Floor, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. E-mail: p.emery@leeds.ac.uk
| The first 10% of the full text of this article appears below. |
SIR, Infliximab, a chimeric monoclonal antibody, has demonstrated effective suppression of disease and prevention of the progression of structural damage in rheumatoid arthritis (RA) in its phase III randomized study (ATTRACT study) [1, 2]. Two anti-tumour-necrosis factor
(TNF-
) drugs, infliximab and etanercept, have recently been approved by the National Institute of Clinical Excellence [3].
With a large number of patients at a single centre for the ATTRACT study [1], the follow-up
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