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Rheumatology 2004; 43: 244
British Society for Rheumatology 2004; all rights reserved

Letter to the Editor

Anti-CD20 monoclonal antibody (rituximab) for refractory autoimmune thrombocytopenia in a girl with systemic lupus erythematosus

R. ten Cate1,2, F. J. Smiers1, R. G. M. Bredius1, A. C. Lankester1, L. W. A. van Suijlekom-Smit2, T. W. Huizinga3 and R. M. Egeler1

1Department of Paediatrics and 3Department of Rheumatology, Leiden University Medical Center and 2Erasmus Medical Center/Sophia Children's Hospital Rotterdam, The Netherlands

Correspondence to: R. ten Cate, Department of Paediatrics, Leiden University Medical Center, Mailbox 9600, 2300 RC Leiden, The Netherlands. E-mail: R.ten_Cate@lumc.nl

The first 10% of the full text of this article appears below.

SIR, Childhood-onset systemic lupus erythematosus (SLE) is a disease with considerable morbidity and mortality [1]. Treatment options, depending on the clinical expression of the disease, include non-steroidal anti-inflammatory drugs, hydroxychloroquine, corticosteroids and cytotoxic agents [2]. For immune thrombocytopenia in children corticosteroids, intravenous immunoglobulins, intravenous anti-D immunoglobulin and splenectomy are used [3. . . [Full Text of this Article]


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