Skip Navigation


Rheumatology Advance Access originally published online on February 10, 2004
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
43/5/596    most recent
keh124v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (27)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Allcock, R. J.
Right arrow Articles by Griffiths, I. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Allcock, R. J.
Right arrow Articles by Griffiths, I. D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Rheumatology 2004; 43: 596-602
Rheumatology Vol. 43 No. 5 (c) British Society for Rheumatology 2004; all rights reserved

Clinical

A study of the prevalence of systemic sclerosis in northeast England

R. J. Allcock, I. Forrest, P. A. Corris, P. R. Crook1 and I. D. Griffiths2

Department of Respiratory Medicine, Freeman Hospital, Newcastle upon Tyne NE7 7DN, 1Department of Rheumatology, Wansbeck General Hospital, Woodhorn Lane, Ashington, Northumberland NE63 9JJ, 2Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne, UK

Correspondence to: R. Allcock, Low Shilford House, Nr Stocksfield, Northumberland NE43 7HW, UK. E-mail: robertallcock{at}onetel.ac.uk

Objectives. We aimed to obtain an estimate of the prevalence and demographics of systemic sclerosis (SSc) and its subtypes at the turn of the millennium.

Methods. Case finding from multiple sources from a defined geographical area. Diagnosis confirmed by clinical examination.

Results. The crude prevalence of SSc in northeast England was 8.8 (95% CI: 6.8–10.8) per 100 000. The prevalence when adjusted for the entire UK is 8.2 (95% CI: 6.2–9.8) per 100 000. The ratio of women to men was 5.2:1. The median age of patients was 57.1 yr. The ratio of limited cutaneous SSc to diffuse cutaneous SSc was 4.7:1. Limited cutaneous SSc is associated with the presence of anticentromere antibodies; diffuse cutaneous SSc is associated with anti-Scl 70 antibodies, but either antibody was found in either form of SSc.

Conclusions. SSc appears to be more common in northeast England than was found in the West Midlands in 1986. This may reflect changes in the diagnostic definition of SSc.

KEY WORDS: Systemic sclerosis, Prevalence, Scleroderma, CREST.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Ann Rheum DisHome page
M C Vonk, B Broers, Y F Heijdra, E Ton, R Snijder, A P J van Dijk, J M van Laar, H Bootsma, P T. W van Hal, F H J van den Hoogen, et al.
Systemic sclerosis and its pulmonary complications in The Netherlands: an epidemiological study
Ann Rheum Dis, June 1, 2009; 68(6): 961 - 965.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.