Rheumatology Advance Access originally published online on January 18, 2005
Rheumatology 2005 44(3):410-411; doi:10.1093/rheumatology/keh503
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Rheumatology Vol. 44 No. 3 © British Society for Rheumatology 2005; all rights reserved
LETTER TO THE EDITOR |
Rituximab inefficiency during type I cryoglobulinaemia
Service de Medecine Interne et dImmunologie Clinique, 1, place de lHôpital, 67091 Strasbourg, France
Correspondence to: H. Nehme-Schuster. E-mail: Helene.Nehme@chru-strasbourg.fr
| The first 10% of the full text of this article appears below. |
SIR, Rituximab, a chimeric antibody binding to the human B-cell antigen CD20, is effective and safe as adjuvant or primary therapy in several B-cell lymphomas. It has also been used in other haematological disorders sustained by B-cell lymphoproliferation and appears promising in some autoimmune diseases. Rituximab also has proved efficiency during type II mixed cryoglobulinaemia (Cg) [1, 2], reducing cryoglobulin levels and significantly improving clinical parameters in
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