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Rheumatology Advance Access originally published online on February 16, 2005
Rheumatology 2005 44(5):684-685; doi:10.1093/rheumatology/keh570
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

LETTER TO THE EDITOR

Corneodesmosin polymorphisms in psoriatic arthritis

C. Butt, P. Rahman, F. Siannis2, V. T. Farewell2 and D. D. Gladman1

St Clare's Mercy Hospital, Memorial University of Newfoundland, St John's, Newfoundland, 1 Center for Prognosis Studies in Rheumatic Diseases, University Health Network, University of Toronto, Toronto, Canada and 2 MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK

Correspondence to: P. Rahman, St Clare's Mercy Hospital, 1 South, 154 LeMarchant Rd, St John's, Newfoundland, Canada A1C 5B8. E-mail: prahman@mun.ca

The first 10% of the full text of this article appears below.

SIR, Based on association studies and genome-wide linkage scans in psoriasis, there is convincing evidence for a major psoriasis susceptibility locus within the MHC complex (reviewed in [1]). The primary area of interest resides in a 200 kb region between HLA-C and corneodesmosin (CDSN) that is in strong linkage disequilibrium (LD). Despite widely reported associations between HLA-Cw0602 and psoriasis, there is ongoing debate about the . . . [Full Text of this Article]


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