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Rheumatology Advance Access originally published online on July 19, 2005
Rheumatology 2005 44(9):1196; doi:10.1093/rheumatology/kei009
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© The Author 2005. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

LETTER TO THE EDITOR

RUNX1 intronic SNP is not associated with rheumatoid arthritis susceptibility in Dutch Caucasians

J. Wesoly, R. E. M. Toes, P. E. Slagboom1 and T. W. J. Huizinga

Department of Rheumatology and 1 Section of Molecular Epidemiology, Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands

Correspondence to: J. Wesoly, Department of Rheumatology, Leiden University Medical Center, Postbus 9600, 2300 RC Leiden, The Netherlands. E-mail: j.z.wesoly@lumc.nl

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SIR, Among a number of genes, RUNX1, a haematopoietic transcription activator and repressor, has been recently identified as a rheumatoid arthritis (RA) susceptibility gene [1]. In order to replicate and confirm this finding, we set out to determine the genotype and allele frequencies of RUNX1 intronic gene variant (rs2268277) in a Caucasian population of RA . . . [Full Text of this Article]


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