Rheumatology Advance Access originally published online on August 18, 2006
Rheumatology 2006 45(10):1308-1309; doi:10.1093/rheumatology/kel271
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© The Author 2006. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
LETTERS TO THE EDITOR |
Associations between cartilage oligomeric matrix protein and several articular tissues in early knee joint osteoarthritis
Department of Laboratory Medicine, Tartu University and 1Department of Radiology, Tartu University Clinics, Estonia
Correspondence to: J. Kumm, L. Puusepa 1A-4022, Tartu 50406, Estonia. E-mail: Jaanika.Kumm@kliinikum.ee
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SIR, Knee osteoarthritis (OA) involves different joint tissues. Nevertheless, main focus has been placed on the changes in articular cartilage. Therefore, components of the cartilage have been studied thoroughly as progression markers for early stage OA [1, 2]. Recently, with the help of the whole panel of cartilage biomarkers, Sharif et al. [3] found that only serum cartilage oligomeric matrix protein (S-COMP) levels differentiated between the subsets of tibiofemoral (TF) and patellofemoral (PF) OA, being higher in the former subset.
However,