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Rheumatology Advance Access originally published online on October 31, 2006
Rheumatology 2006 45(12):1570-1571; doi:10.1093/rheumatology/kel319a
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© The Author 2006. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Autologous haematopoeitic stem cell rescue (AHSCR) for severe rheumatic disease in children

Guidance for BSPAR members—executive summary

H. Foster1, J. Davidson2, E. Baildam3, M. Abinun4, L. R. Wedderburn5 on behalf of the British Society for Paediatric and Adolescent Rheumatology

1Newcastle University, Newcastle-upon-Tyne, 2Yorkhill Children's Hospital NHS Trust, Glasgow, 3Royal Liverpool Children's Hospital NHS Trust, Liverpool, 4Newcastle Hospitals NHS Trust, Newcastle-upon-Tyne, and 5University College London and Great Ormond Street Hospital NHS Trust, London, UK.

Correspondence to: Dr H. Foster, School Clinical Medical Science (Rheumatology), Medical School, Framlington Place, Newcastle-upon-Tyne NE2 4HH. E-mail: h.e.foster@ncl.ac.uk

The first 10% of the full text of this article appears below.


    Scope and purpose
 
Autologous haematopoeitic stem cell rescue (AHSCR) is a treatment option for children with severe rheumatic disease and to date most experience is with juvenile idiopathic arthritis (JIA) [1–6]. Currently two transplant centres in the UK have NSCAG (National Specialist Commissioning Advisory Group) funding to perform AHSCR for children with severe rheumatic disease; these are Newcastle (Newcastle General Hospital) and London (Great Ormond Street), both of which follow latest protocols set with the Joint European Bone Marrow Transplant (EBMT) and European Society for Immunodeficiency (ESID) Working Party Sub-Committee (www.esid.org),and submit patients to the EBMT Registry. In the absence . . . [Full Text of this Article]


    The guideline itself
 
1. The process of patient selection, independent assessment and referral to the transplant team
1.1 The selection of patients.
1.2 The referral for independent assessment
1.3 The referral to a Transplant Centre and the AHSCR procedure (including pre- and post-AHSCR care)
2. The roles of the ‘stakeholders’
2.1 The roles of the referral team
2.2 The roles of the independent assessor.
2.3 The roles of the transplant team

    Practical aspects of this guideline
 

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