Rheumatology Advance Access originally published online on March 14, 2006
Rheumatology 2006 45(5):637-640; doi:10.1093/rheumatology/kel079
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© The Author 2006. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
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Two- and three-dimensional Doppler sonographic evaluation of the effect of local cryotherapy on synovial perfusion in wrist arthritis
Department of Rheumatology and Clinical Immunology, Kerckhoff Clinic and University of Giessen, Benekestrasse 2-8, 61231 Bad Nauheim.
Correspondence to: J. Strunk, MD, Department of Rheumatology and Clinical Immunology, Kerckhoff Clinic and University of Giessen, Benekestrasse 2-8, 61231 Bad Nauheim, Germany. E-mail: j.strunk@kerckhoff-klinik.de
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SIR, Physical treatment including local cold and heat application has been used since antiquity in patients with arthritis. Both methods are known to relieve pain and improve disability in different stages of various rheumatic diseases. An analgesic effect can be readily accomplished after 3 min of local cryotherapy by destimulating pain receptors, which are located in the subcutis. Antiphlogistic effects are obtained after cold application for 20 min and longer by vasoconstriction, by inhibiting the cellular metabolism in the inflammatory cells and by repressing the release of lysosomal enzymes [1,
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