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Rheumatology Advance Access originally published online on September 5, 2007
Rheumatology 2007 46(10):1615-1616; doi:10.1093/rheumatology/kem146a
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

BSR and BHPR guidelines for the management of adults with ANCA associated vasculitis

C. Lapraik1, R. Watts2,3, P. Bacon4, D. Carruthers5, K. Chakravarty6, D. D’Cruz7, L. Guillevin8, L. Harper9, D. Jayne10, R. Luqmani11, J. Mooney12, D. Scott1,2, on behalf of the BSR and BHPR Standards, Guidelines and Audit Working Group

1Department of Rheumatology, Norfolk and Norwich University Hospital, Norwich, 2School of Medicine Health Policy and Practice, University of East Anglia, Norwich, UK, 3Department of Rheumatology, Ipswich Hospital NHS Trust, Ipswich, UK, 4Department of Rheumatology, University of Birmingham, Birmingham, UK, 5Department of Rheumatology, City Hospital, Birmingham, UK, 6Department of Rheumatology, Harrold Wood Hospital, London, UK, 7Department of Rheumatology, St Thomas's; Hospital, London, UK, 8Department of Internal Medicine, Hopital Cochin, Universite Paris-Rene-Descartes, France, 9Department of Nephrology, Queen Elizabeth Hospital, Birmingham, UK, 10Department of Nephrology, Addenbrooke's; Hospital, Cambridge, UK, 11Department of Rheumatology, Nuffield Orthopaedic Centre and University of Oxford, Oxford, UK and 12School of Nursing and Midwifery, University of East Anglia, Norwich, UK.

Correspondence to: Dr Richard Watts, Consultant Rheumatologist, Ipswich Hospital NHS Trust, Heath Road, Ipswich IP4 5PD, UK. E-mail: Richard.watts@ipswichhospital.nhs.uk

KEY WORDS: Vasculitis, Guideline, Management, Cyclophosphamide

The first 10% of the full text of this article appears below.


   Executive summary
 
Scope and purpose of the guideline
The ANCA associated vasculitides (AAV) comprise are a group of conditions characterized by inflammation and necrosis of small and medium-sized blood vessels. They comprise Wegener's granulomatosis, Churg–Strauss syndrome and microscopic polyangiitis. Early diagnosis and treatment is important as the presence of advanced disease at diagnosis limits the potential benefit of therapy. The aim of this document is to provide guidelines for the management of adults with systemic vasculitis. The guidelines concentrate on the indications for using cyclophosphamide and the different therapeutic regimens available. The guideline does not cover the treatment of children or other types of systemic . . . [Full Text of this Article]


   Guideline for the management of adults with ANCA-associated vasculitis
 
Eligibility criteria
Exclusion criteria
Treatment

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