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Rheumatology Advance Access originally published online on January 10, 2007
Rheumatology 2007 46(4):716-717; doi:10.1093/rheumatology/kel416
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Progressive osseous heteroplasia: a rare case of late onset

R. Seror, C. Job-Deslandre and A. Kahan

Université Paris-Descartes, Faculté de Médecine, Assistance Publique-Hopitaux de Paris Hôpital Cochin- Service de rhumatologie A – 27 rue du Faubourg Saint Jacques – 75014, Paris, France

Correspondence to: Dr C. Job-Deslandre, Departement of Rheumatology A, Hôpital Cochin, 27 rue du Faubourg Saint Jacques–75014, Paris, France. E-mail: chantal.deslandre@cch.aphp.fr

The first 10% of the full text of this article appears below.

SIR, Progressive osseous heteroplasia (POH) is a rare inherited ossifying disorder of infancy, characterized by diffuse cutaneous and deep connective tissue ossifications. We report a rare case of POH that appeared in adulthood.

In April 2001, a 52-yr-old woman, with no familial history of abnormal ossification, was admitted for pain and stiffness of the lower limbs. She first experienced symptoms in 1985, with knee, calf and ankle pains, and later suffered from lower limb stiffness.

Physical examination revealed subcutaneous ossifications of the lower . . . [Full Text of this Article]


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