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Rheumatology Advance Access originally published online on September 27, 2008
Rheumatology 2008 47(12):1792-1794; doi:10.1093/rheumatology/ken355
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Accuracy of intra-articular injections in peripheral joints performed blindly in patients with rheumatoid arthritis

R. V. Lopes1, R. N. V. Furtado1, L. Parmigiani1, A. Rosenfeld2, A. R. C. Fernandes2 and J. Natour1

1Division of Rheumatology and 2Department of Radiology, Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo, Brazil.

Correspondence to: J. Natour, Disciplina de Reumatologia, Universidade Federal de São Paulo, Rua Botucatu, 740, 04023-900 - São Paulo, Brazil. E-mail: jnatour{at}unifesp.br


   Abstract

Objectives. To assess the accuracy of blind IA injections (IAIs) in patients with RA and determine their effectiveness.

Methods. A controlled prospective study including 96 RA patients undergoing blind IAIs in peripheral joints was carried out. Clinical evaluation was performed at baseline (T0), 1 (T1) and 4 (T4) weeks after IAI using the following instruments: visual analogue scale (VAS) for pain at rest and movement, VAS for oedema (range 0–10 cm) and morning stiffness. Following IAI, radiographic exam was performed in all joints for further analysis by two ‘blinded’ radiologists. The {kappa}-statistic, chi-square and analysis of variance tests were performed to determine potential differences between time-points of evaluation. Significance level was set as P < 0.05.

Results. A total of 232 injections were performed. Accuracy observed for the shoulder, elbow, wrist, MCP joints, knee and ankle were 82, 100, 97, 97, 100 and 77%, respectively. A statistically significant improvement was observed for all variables at both T1 and T4 when compared with T0.

Conclusions. Blind IAI proved safe and accurate when performed by a trained professional. Significant improvement was seen in the VAS for pain at rest and during movement, VAS for oedema and morning stiffness.

KEY WORDS: Rheumatoid arthritis, Intra-articular injection, Arthritis, Corticosteroid, Injections, Accuracy

Submitted 5 February 2008; revised version accepted 30 July 2008.
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