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Rheumatology Advance Access originally published online on December 20, 2007
Rheumatology 2008 47(2):117-118; doi:10.1093/rheumatology/kem334
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

EDITORIAL

Arterial elasticity: asset or liability?

H. MacIver and H. A. Bird

Academic Unit of Musculoskeletal Disease, University of Leeds, UK

Correspondence to: H. A. Bird, Professor of Pharmacological Rheumatology, Musculoskeletal Medicine, Chapel Allerton Hospital, Chapeltown Road, Leeds LS7 4SA, UK. E-mail: howard.bird@leedsth.nhs.uk

The first 150 words of the full text of this article appear below.

That inflammatory polyarthritis and cardiovascular disease are closely related is now undoubted. Even with myocardial infarction and congestive heart failure as surrogates of molecular change, there is a significantly higher frequency of cardiovascular disease in RA compared with age- and sex-matched control individuals [1, 2]. The late John Cosh, in his time the only rheumatologist to hold a joint appointment with cardiology, followed his cohort of 100 patients with RA, recruited upon his appointment, for over 25 yrs to provide prospective confirmation that between one-third and one-half of all RA-related deaths are directly attributable to cardiovascular disease [3]. This was in a cohort of patients not specifically selected for vasculitic features, might have caused this proportion to climb even higher. Collaboration with other disciplines has continued, to the benefit of rheumatology. A striking recent collaboration is the joint funding by the Arthritis Research Campaign and . . . [Full Text of this Article]


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